Exacerbation

1. n. A periodical increase of violence in a disease, as in remittent or continious fever; an increased energy of diseased and painful action.
2. n. The act rendering more violent or bitter; the state of being exacerbated or intensified in violence or malignity; as, exacerbation of passion.

The word meanings were obtained from OPTED(The Online Plain Text English Dictionary), which is based on “The Project Gutenberg Etext of Webster’s Unabridged Dictionary” which is in turn based on the 1913 US Webster’s Unabridged Dictionary (See Project Gutenburg), as a text file.